Artículo de revista
Relationship between mechanical and metabolic dyssynchrony with left bundle branch block: Evaluation by 18-fluorodeoxyglucose positron emission tomography in patients with non-ischemic heart failure
Fecha
2012Registro en:
Journal of Heart and Lung Transplantation, Volumen 31, Issue 10, 2018, Pages 1096-1101
10532498
15573117
10.1016/j.healun.2012.07.002
Autor
Castro, Pablo
Winter, José Luis
Verdejo, Hugo
Orellana, Pilar
Quintana, Juan Carlos
Greig, Douglas
Enríquez, Andrés
Sepúlveda, Luis
Concepción, Roberto
Sepúlveda, Pablo
Rossel, Victor
Chiong Lay, Mario
García Nannig, Lorena
Lavandero González, Sergio
Institución
Resumen
Background: Ventricular dyssynchrony is a common finding in patients with heart failure (HF), especially in the presence of conduction delays. The loss of ventricular synchrony leads to progressive impairment of contractile function, which may be explained in part by segmental abnormalities of myocardial metabolism. However, the association of these metabolic disarrangements with parameters of ventricular dyssynchrony and electrocardiography (ECG) findings has not yet been studied. Methods: Our aim was to determine the correlation between the presence of left bundle branch block (LBBB) with left ventricular (LV) mechanical synchrony assessed by multiple-gated acquisition scan (MUGA) and with patterns of 18-fluorodeoxyglucose (18FDG) uptake in patients with non-ischemic heart failure. Twenty-two patients with non-ischemic cardiomyopathy, LV ejection fraction (LVEF) ≤45% and New York Heart Association (NYHA) Functional Class II or III symptoms under standard medical therapy were included