Artículos de revistas
Gibberellin biosynthesis in plants and fungi: A case of convergent evolution?
Fecha
2001Registro en:
Journal of Plant Growth Regulation, Volumen 20, Issue 4, 2018, Pages 319-331
07217595
10.1007/s003440010037
Autor
Hedden, Peter
Phillips, Andrew L.
Rojas, Maria Cecilia
Carrera, Esther
Tudzynski, Bettina
Institución
Resumen
As well as being phytohormones, gibberellins (GAs) are present in some fungi and bacteria. Indeed, GAs were first discovered in the fungus Gibberella fujikuroi, from which gibberellic acid (GA3) and other GAs are produced commercially. Although higher plants and the fungus produce structurally identical GAs, there are important differences in the pathways and enzymes involved. This has become particularly apparent with the identification of almost all of the genes for GA-biosynthesis in Arabidopsis thaliana and G. fujikuroi, following the sequencing of the Arabidopsis genome and the detection of a GA-biosynthesis gene cluster in the fungus. For example, 3β-hydroxylation occurs early in the pathway in G. fujikuroi and is catalyzed by a cytochrome P450 monooxygenase, whereas it is usually the final step in plants and is catalyzed by 2-oxoglutarate-dependent dioxygenases. Similarly, 20-oxidation is catalyzed by dioxygenases in plants and a cytochrome P450 in the fungus. Even where cytochr