Artículo de revista
Distribution of pneumocystis carinii f. sp. hominis types in the lung of a child dying of pneumocystis pneumonia
Fecha
2001Registro en:
Clinical Infectious Diseases 2001 Volumen: 33 Número: 9 Páginas: E100-E102
10.1086/322690
Autor
Ambrose, Helen E.
Ponce, Carolina A.
Wakefield, Ann E.
Miller, Robert F.
Vargas Munita, Sergio
Institución
Resumen
Pneumocystis f. sp. hominis causes pneumonia in immunocompromised persons. In order to determine the types and distribution of P. carinii organisms within a single human lung, multiple samples were obtained from the lung of a child who died of P. carinii pneumonia. P. carinii DNA was detected in all of the samples and 2 different genotypes of P. carinii were identified, with uneven distribution in the lung, demonstrating that infection of the human lung is not necessarily clonal, and that differentP.cariniigenotypesmay predominate in different areas of the lung.