Artículo de revista
Developmental and Functional Effects of Steroid Hormones on the Neuroendocrine Axis and Spinal Cord
Fecha
2016Registro en:
Journal of Neuroendocrinology, 2016, 28(7)
0953-8194
10.1111/jne.12401
Autor
Zubeldia Brenner, L.
Roselli, C. E.
Recabarren, S. E.
González, M. C.
Lara Peñaloza, Hernán
Institución
Resumen
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual orientation, reproductive and metabolic programming, and the neuroendocrine mechanism involved in the development of polycystic ovary syndrome phenotype. Moreover, consistent with the wide range of processes in which steroid hormones take part, we discuss the protective effects of progesterone on neurodegenerative disease and the signalling mechanism involved in the genesis of oestrogen-induced pituitary prolactinomas