Artículos de revistas
Immune response modulation by vitamin D: role in systemic lupus erythematosus
Fecha
2015Registro en:
Frontiers in Immunology | October 2015 | Volume 6 | Article 513
doi: 10.3389/fimmu.2015.00513
Autor
Iruretagoyena, Mirentxu
Hirigoyen, Daniela
Naves Pichuante, Rodrigo Antonio
Isabel Burgos, Paula
Institución
Resumen
Vitamin D plays key roles as a natural immune modulator and has been implicated in the pathophysiology of autoimmune diseases, including systemic lupus erythematosus (SLE). This review presents a summary and analysis of the recent literature regarding immunoregulatory effects of vitamin D as well as its importance in SLE development, clinical severity, and possible effects of supplementation in disease treatment.