Artículo de revista
Effect of Casein-Derived Peptides on D-Xylose Absorption Assessed by H2 Breath Test in Normal Volunteers
Fecha
2000-04Registro en:
Digestive Diseases and Sciences, Vol. 45, No. 4 (April 2000), pp. 705–709
Autor
Defilippi Cafri, Carlos
Madrid Silva, Ana
Salas, Karime
Michea Acevedo, Luis
Lagos Wilson, Néstor
Institución
Resumen
Studies have shown a promoting effect of food on small intestinal absorption. Casein
hydrolysate seems be more effective in increasing of D-xylose absorption in dogs than the
whole protein and lactulose. The purpose this study was to analyze the effect of groups of
peptides derived from casein hydrolysate on the absorption of D-Xylose and intestinal transit
time in normal subjects. Seven normal volunteers participated in the study. Three peptide
fractions were isolated from casein enzymatic hydrolysate by means of a preparative HPLC
silica column. On separate days subjets drank test solutions containing lactulose, D-xylose,
and D-xylose with one of three peptide groups. The hydrogen breath test was used to
indirectly estimate D-xylose absorption and orocecal transit time. Two peptide fractions when
added to D-xylose were followed by an increased absorption characterized by decreased H2
production. A nonstatistically significant increase of orocecal transit time was observed with
these peptides.