Artículo de revista
Detection of Pneumocystis carinii f. sp hominis and viruses in presumably immunocompetent infants who died in the hospital or in the community
Fecha
2005-06-01Registro en:
JOURNAL OF INFECTIOUS DISEASES
0022-1899
Autor
Vargas Munita, Sergio
Ponce, Carolina A.
Luchsinger Farías, Vivian
Silva, Cecilia
Gallo, Myriam
López, René
Belletti, José
Velozo Papez, Luis
Avila, Ricardo
Palomino Montenegro, María Angélica
Benveniste Dinar, Samuel
Avendaño, Luis Fidel C.
Institución
Resumen
Fresh-frozen lung and tracheal-aspirate specimens obtained from 112 infants who died in Santiago, Chile, during 1998-2000 were analyzed for the presence of Pneumocystis DNA, by use of nested DNA amplification of the large subunit mitochondrial rRNA, and for the presence of viruses, by use of culture and immunofluorescence. Pneumocystis DNA was detected in specimens from 45 (51.7%) of 87 infants who died in the community and from 5 (20%) of 25 infants who died in the hospital (P = .006). Primary infection with PneumoPp. cystis was highly frequent among infants who die unexpectedly in the community. Infection with viruses was more common in infants who died in the hospital.