Artículos de revistas
Evaluation of the efficacy of two mouthrinses formulated for the relief of xerostomia of diverse origin in adult subjects
Fecha
2012Registro en:
Gerodontology 2012; 29: e1103–e1112
doi: 10.1111/j.1741-2358.2012.00626.x
Autor
Morales Bozo, Irene
Urzúa Orellana, Blanca
Rojas Alcayaga, Gonzalo
Ortega Pinto, Ana
Espinoza Santander, Iris
Soto Sáez, Lilian
Plaza, Anita
Lozano, Carla
Institución
Resumen
Objective: To evaluate the efficacy of two new mouthrinses in the reduction of xerostomı´a-associated
symptomatology.
Background: Xerostomia is a common chronic health condition that affects a great number of adults and
significantly deteriorates quality of life, such that treatment is necessary.
Materials and methods: Sixty-seven adult subjects of both sexes presenting xerostomia of diverse origin
were selected. Mouthrinses were tested using a double-blind, randomized, cross-over clinical trial with an
intervining wash out period.
Results: The 100% of subjects presented sensation of dry mouth, and 86% stated sensation of thick saliva.
Burning tongue sensation, need to drink liquids to swallow and the sensation of swallowing difficulty were
recorded in more than 50% of the patients. The most frequent pathologies in the sample were depression,
arthritis, and arterial hypertension. Results of the clinical tests showed that mouthrinse 1 relieves sensation
of dry mouth, need to drink liquids, and swallowing difficulty. In contrast, mouthrinse 2 relieves only latter
two symptoms. Both rinses were more effective in relieving xerostomı´a-associated symptomatology in
patients taking 3 or more medicines simultaneously.
Conclusion: Both mouthrinses were effective in relieving various xerostomia symptoms, could be
distributed at a low cost, thereby improving the quality of life of population affected.