Artículos de revistas
Synthesis of 1-benzyl-3-[4-(aryl-1-piperazinyl) carbonyl]-1H-indoles. Novel ligands with potential D4 dopaminergic activity
Fecha
2011Registro en:
J. Chil. Chem. Soc., 56, Nº 4 (2011)
Autor
Pessoa Mahana, Hernán
Cuevas M., Ignacio
Pessoa Mahana, Carlos David
Araya Maturana, Ramiro
Almodovar, Iriux
Saitz Barría, Claudio
Institución
Resumen
The synthesis of a series of functionalized 1-Benzyl-3-[4-Aryl-1-piperazingl]carbonyl-1H-Indoles 6(a-f), as a potential new class of bioactive ligands at D4 receptors is reported. The synthetic strategy took place through a five steps sequence to provide indole amides 6(a-f) in 75-92% yield.