Solvent-free microwave synthesis of 3-(4-benzo[b]thiophene-2-carbonyl)-1-piperazinyl-1-benzo[b]thiophen-2-yl-1-propanones. New hetero bis-ligands with potential 5-HT1A serotonergic activity

dc.creatorPessoa Mahana, Hernán
dc.creatorKosche Cárcamo, Johann Albert
dc.creatorRon Higuera, Nadia Betsabé
dc.creatorRecabarren Gajardo, Gonzalo Iván
dc.creatorSaitz Barría, Claudio
dc.creatorPessoa, D.
dc.creatorAraya Maturana, Ramiro
dc.date.accessioned2009-08-25T16:28:40Z
dc.date.accessioned2019-04-25T23:28:30Z
dc.date.available2009-08-25T16:28:40Z
dc.date.available2019-04-25T23:28:30Z
dc.date.created2009-08-25T16:28:40Z
dc.date.issued2008-08-01
dc.identifierHETEROCYCLES 75(8): 1913-1929
dc.identifier0385-5414
dc.identifierhttp://repositorio.uchile.cl/handle/2250/120777
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/2425132
dc.description.abstractA novel series of 2-benzothiophenealkylpiperazine derivatives 11 (a-d) with potential affinity at 5-HT1A serotonin receptors have been synthesized via solvent-free, microwave-promoted Michael addition of benzo[b]thiophene piperazine derivatives 6(a-c) to substituted benzo[b]thiophen-2-yl propenones 10(b,c).
dc.languageen
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD
dc.subjectMichael addition
dc.titleSolvent-free microwave synthesis of 3-(4-benzo[b]thiophene-2-carbonyl)-1-piperazinyl-1-benzo[b]thiophen-2-yl-1-propanones. New hetero bis-ligands with potential 5-HT1A serotonergic activity
dc.typeArtículos de revistas


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