Artículos de revistas
THE USE OF COMPETlTlVE LIGAND BINDING RESULTS IN QSAR STUDIES
Fecha
1984-06-28Registro en:
IL FARMACO EDIZIONE SCIENTIFICA, vol. 40 . fasc. 5, Mayo, 1985.
0430-0920
Autor
Gómez Jeria, Juan
Institución
Resumen
The use in QSAR studies of parameters measuring the
ability of an unlabeled rnolecule to compete for the binding site with a
. radioligand is examined.
1t is shown that in order to employ them within a recently developed
formal model it is previously necessary to carry out a linear transformation.
This necessarily demands the adoption by investigators of a standard measuring
procedure.