QUANTUM CHEMICAL STUDY OF ELECTRONIC-STRUCTURE AND RECEPTOR-BINDING IN OPIATES

dc.creatorGómez Jeria, Juan
dc.creatorSotomayor, P.
dc.date.accessioned2011-11-10T20:45:58Z
dc.date.available2011-11-10T20:45:58Z
dc.date.created2011-11-10T20:45:58Z
dc.date.issued1988
dc.identifierTHEOCHEM-JOURNAL OF MOLECULAR STRUCTURE, Volume: 43, Pages: 493-498, 1988
dc.identifier0166-1280
dc.identifierhttps://repositorio.uchile.cl/handle/2250/119359
dc.description.abstractA Quantitative Structure-Activity Relationship study for a group of opiates interacting with the mu receptor was carried out. The study consisted in searching a relationship between the drug-receptor equilibrium constant and steric/ electronic structure factors. Several equations were obtained and analyzed. It is possible to conclude from this study that if all the experimental values correspond only to the interaction with the mu receptor, then the hypothesis of a comben skeleton interacting with the mu receptor cannot be supported.
dc.languageen
dc.publisherELSEVIER SCIENCE BV
dc.titleQUANTUM CHEMICAL STUDY OF ELECTRONIC-STRUCTURE AND RECEPTOR-BINDING IN OPIATES
dc.typeArtículo de revista


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