Artículos de revistas
Microbial transformation of the diterpene mulin-11,13-dien-20-oic acid by Mucor plumbeus
Fecha
2008-08Registro en:
MAGNETIC RESONANCE IN CHEMISTRY Volume: 46 Issue: 8 Pages: 765-768 Published: AUG 2008
0749-1581
10.1002/mrc.2238
Autor
Areche Medina, Carlos
Loyola, Luis Alberto
Bórquez, Jorge
Rovirosa, Juana
San Martín Barrientos, Aurelio
Institución
Resumen
Two new mulinane-type derivatives: 16-hydroxy mulin-11,13-dien-20-oic (2) acid and 7 alpha,16-dihydroxy mulin-11,13-dien-20-oic (3) acid were obtained by microbial transformation of mulin-11,13-dien-20-oic acid (1), along with tyrosol (4) using liquid cultures of Mucor plumbeus. The latter compound has not been previously identified in the genus Mucor. Structural elucidation of these metabolites was achieved using 1D- and 2D-NMR spectroscopy.