Artículos de revistas
Synthesis of 2-aryl-1,3-propanediamines using a one-pot Knoevenagel-Michael sequence
Fecha
2006-03Registro en:
JOURNAL OF THE CHILEAN CHEMICAL SOCIETY Volume: 51 Issue: 1 Pages: 781-783 Published: MAR 2006
0717-9324
Autor
Iturriaga-Vásquez, Patricio
Lühr Sierra, Susan
Caroli Rezende, Marcos
Cassels Niven, Bruce
Institución
Resumen
A simple synthetic route for the preparation of 2-phenyl-1,3-propanediamines, based on a Knoevenagel-Michael double condensation followed by reduction, was developed using nitromethane as reagent and solvent, and sodium bicarbonate as base in the first step, followed by catalytic hydrogenation over Adams catalyst.