masterThesis
Utilidad de las tiras reactivas para el diagnóstico temprano de Peritonitis Bacteriana Espontánea en pacientes cirróticos
Fecha
2017Autor
Bejarano Rengifo, Janeth
Institución
Resumen
Introduction. Spontaneous bacterial peritonitis (SBP) requires an early diagnosis for the initiation of antibiotic therapy. The diagnosis is based on cytochemical examination of ascitic fluid, which takes hours to perform and has limited availability 24 hours a day, especially in first level hospitals and in rural areas. We evaluated the utility and diagnostic accuracy of Multistix 10SG reagent strip for diagnosis of SBP in cirrhotic patients with ascites admitted in Cardioinfantil Foundation –Cardiology Institute. Materials and methods. Diagnostic test study in cirrhotic patients with ascites. The leucocyte count of ascitic fluid was determined by colorimetric scale of Multistix 10SG reagent strips and was compared with the gold standard for the diagnosis of SBP (polymorphonuclear (PMN) ≥ 250 cells / mm³). Results. Of 106 patients with ascites (51.8% men, mean age 59 years) 16 patients were diagnosed with SBP. The sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio taking grade ++ as cut off were 93.7%, 95.5%, 78.9%, 98%, 21 and 0.06, respectively. Conclusions. Multistix 10SG reagent strip has a high sensitivity and specificity for the diagnosis of PBE compared to PMN count method. It is a inexpensive and easy technique, requires minimal time for interpretation and is available, even in remote areas. This test may be useful for the diagnosis of SBP in country like Colombia