article
Un análisis de los efectos ansiolíticos del etanol sobre el contraste negativo sucesivo consumatorio
An analysis of the anxiolytic effects of ethanol on consummatory successive negative contrast
Autor
Kamenetzky, Giselle V.
Mustaca, Alba Elisabeth
Papini, Mauricio Roberto
Institución
Resumen
The anxiolytic properties of ethanol (1 g/kg, 15% dose, i.p.) were studied in two experiments with rats involving incentive downshifts from a 32% to a 4% sucrose solution. In Experiment 1, alcohol administration before a downshift from 32% to 4% sucrose prevented the development of consummatory suppression (consummatory successive negative contrast, cSNC). In Experiment 2, ethanol prevented the attenuating effects of partial reinforcement (random sequence of 32% sucrose and nothing) on cSNC, causing a retardation of recovery from contrast. These effects of ethanol on cSNC are analogous to those described for the benzodiazepine anxiolytic chlordiazepoxide, suggesting that at least some of its anxiolytic effects are mediated by the same mechanisms.