masterThesis
Uso de lisados bacterianos en la prevención de la infección respiratoria recurrente en pediatría. Revisión sistemática de la literatura
Fecha
2012Autor
Rodriguez Ossa, Sandra Patricia
Aguilera Martinez, Sara
Institución
Resumen
The upper and lower respiratory infections are a common cause of childhood morbidity and mortality. It has proposed the use of bacterial lysates to prevent recurrent infections even though their use is considered controversial.
Methodology: We conducted a systematic review of the literature. The search was performed using the databases PubMed, Embase, Ovid, Lilacs and Cochrane Library. We included meta-analyzes published in English and Spanish, between 1998 and 2012. An evaluation of quality following the strategy Quorum and qualitative and quantitative analysis of the results.
Results: We included 4 systematic reviews of the literature with meta-analysis. Was appreciably reduced recurrences of respiratory infections related to the use of bacterial lysates. The bacterial lysates reduce the need for antibiotics. There was no evidence on the use of the lysates on outcomes such as the need for additional interventions, length of stay, costs related to health care. There were no significant adverse events.
Conclusion: The bacterial lysates are effective in reducing the recurrence of respiratory infections in pediatric patients.