masterThesis
Factores de riesgo para transfusión intraoperatoria de globulos rojos en trasplante hepático en la Fundación Cardioinfatil
Fecha
2018Autor
Ballen Tole, Manuel Camilo
Institución
Resumen
Introduction: Liver transplant is a salvage procedure in patients with terminal liver pathology. Hemorrhage with requirement of red blood cell (RBC) transfusion is a common complication associated with increased morbidity and mortality. Objective: To Recognize risk factors associated with intraoperative use of RBC transfusion in adult patients undergoing liver transplantation at CardioInfantil Foundation Center. Method: Sample population consists of patients who required orthotopic liver transplant between 2013-2017. A case control study was performed. the group of patients undergoing the procedure was divided between patients who required RBC transfusion and those who did not require RBC transfusion, risk factors and strategies that could decrease RBC transfusion were analyzed. Results: 190 procedures were included, RBC transfusion requirement frequency was 54,2%; after multivariate analysis and contrary to previous publications, use of cell saver was a risk factor RBC transfusion. Like results reported by other liver transplant groups anhepatic phase more than 50 minutes, donor age more than 39,5 years old and hemoglobin (hb) greater than 12,6 g/dl were protector variables for RBC transfusion. Discussion: To optimize morbidity and mortality of patients undergoing liver transplantation, hb must be optimized.