bachelorThesis
Índice de pulsatilidad de arteria cerebral media como predictor para desenlaces desfavorables en fetos pequeños para la edad gestacional
Fecha
2014Autor
Bonilla Cortés, Leonardo
Sánchez Gutierrez, Sandra Milena
Institución
Resumen
Introduction Thepresence of isolated vasodilatation middle cerebral artery in small for gestational age fetuses with no other changes in the doppler, can be interpreted as physiological or could be the initial manifestation of late intrauterine growth restriction. We sought to evaluate the association of decreased pulsatility index in the middle cerebral artery as a predictor of adverse perinatal outcomes in fetuses with low weight for gestational age.
Methodology: A cohort study of analytical historical temporality was performed to determine whether the finding of decreased pulsatility in the middle cerebral artery is associated with adverse perinatal outcome in small for gestational age fetuses using a non-probability sampling.
Results: A total of 325 doppler studies of small fetuses were collected. The risk of preterm delivery was RR 2.6 95% CI 1.6-4.1 , hospitalization was RR 1.4 95% CI 1.1-1.9 and death was 2.1 95% CI 1.5-3.2 with disruption in the middle cerebral artery. Logistic regression showed that the risk of unfavorable outcomes is RR 4.2 95% CI 2.5-7.1 with changes in the middle cerebral artery adjusted for maternal age, gestational age and low birth weight.
Discussion Exposed patients are at a higher risk of unfavorable outcomes with significant differences, not in other published studies. This study shows significant associations that should be evaluated in larger studies..
Keywords: Small for gestational age, middle cerebral artery vasodilation , IUGR