masterThesis
Efectos del parto prematuro y retraso en el crecimiento fetal sobre los factores de riesgo cardiovascular durante el curso de la vida entre niños y adolescentes de escuelas oficiales de Bogotá, Colombia: Estudio FUPRECOL
Fecha
2017Autor
Becerra Narváez, Ibelice
Institución
Resumen
Background: Both fetal growth restriction and prematurity have been associated with cardiometabolic risk in youth and adults, however, their combined effects on youth cardiometabolic health are scarce. Aims: This study aimed at assessing the effects of birth weight and gestational age combined on life-course cardiovascular risk factors and obesity among schoolchildren from Colombia. Study design: A cross-sectional study. Subjects: Participants comprised 2, 510 Colombian schoolchildren (54. 8% girls) aged 9-17. 9 years. Outcome measures: Four groups were created according to WHO criteria: those born at term with an appropriate birth weight (≥ 2, 500g to ≤ 4, 000g) for gestational age (term AGA); those born preterm (< 37 to < 42 completed weeks) with an appropriate birth weight for gestational age (preterm AGA); those born at term with low birth weight for gestational age (term SGA); and those born preterm with low birth weight for gestational age (preterm SGA). Anthropometric markers (body mass, height, waist circumference, and body mass index), blood pressure, lipids profile, fasting glucose, and pubertal stage were assessed. The prevalence of metabolic syndrome was determined by de Ferranti definition. Results: There were differences between groups for age (p=0. 011), body mass (p=0. 001), height (p=0. 001), and body mass index (p=0. 027). Overall, preterm SGA group had a greater risk for having elevated fasting glucose and metabolic syndrome (total sample and in boys) compared with term AGA group (p< 0. 05). For other cardiovascular risk factors, no significant relationships were observed based on birth characteristics. Conclusions: School-age children and adolescents with combined fetal growth restriction and prematurity exhibited an increased prevalence of glucose risk and metabolic syndrome.