masterThesis
Eficacia del factor estimulante de colonias de granulocitos en el manejo de la enterocolitis neutropénica en pediatría
Fecha
2012Autor
Casas Anillo, Carolina
Flechas Afanador, Jessica
Institución
Resumen
Background: Neutropenic enterocolitis is a complication that occurs in children receiving chemotherapy. It has been proposed the use of granulocyte colony-stimulating factor as a treatment. However, no systematic reviews have been developed to assess its effectiveness.
Objective: To determine the efficacy of the use of granulocyte colony-stimulating factor handling neutropenic enterocolitis.
Methodology: We conducted a systematic review of the literature with clinical trials search through the databases Pubmed, Cochrane, Embase, Ovid and Bireme. As limits were English and Spanish and publication between 1996 and 2012. We proposed to perform a quality analysis using the Cochrane Collaboration's recommendation. It was raised performing a meta-analysis of literature.
Results: No available studies that explore the effectiveness of colony-stimulating factor in children and adolescents with neutropenic enterocolitis were found.
Conclusion: We can not make a judgment of positive or negative factor in the effectiveness of the management of neutropenic enterocolitis in children or adolescents. We have no evidence to evaluate the use of colony-stimulating factor in pediatric patients with neutropenic enterocolitis.