bachelorThesis
Morbimortalidad, función ventricular e incidencia del rechazo celular en el trasplante cardíaco en la Clínica Abood Shaio
Fecha
2012Registro en:
TEME 0080 2011
Autor
Páez Lesmes, Guillermo
Institución
Resumen
INTRODUCTION: Heart transplantation in an effective therapy for patients with terminal heart failure. There are currently no Colombian records updated and published in morbidity and mortality of heart transplantation in relation to episodes of cellular rejection.
MATERIALS AND METHODS: A descriptive retrospective study of patients older than 18 years transplanted in Shaio Clinic. Frequency calculations were performed, averages, and Kaplan Meier survival.
RESULTS: The average age was 46.7 years + / - 13.The indications were idiopathic cardiomyopathy with 45%, coronary 30%, myocarditis 9%, Chagas 9% valvular 7%. The cellular in the first three years : 57%, 54% 41% decrease to 25% between three and five years . The causes of death were failure of transplantation 46%, infections and heart failure 23%, reject 8 %. The first year the mortality rate was 65%, mainly the graft failure. Mortality at 30 Days 29.5% and survival was 90 % at 1 year, 64% at 5 years, 48% at 10 years and 15% at age of 13. The median survival was 8 years old. The vascular disease was 33%. Left ventricular function 53.5% +/-12.6 the first year; 58.4 +/-5.4% in the third year; 51.7 +/-11.9% the fifth year 46% +/-15.8 to the tenth year.
DISCUSSION: Note increased frequency of cellular rejection, causing more cardiac failure and death.