The Coulomb effects hypothesis is used to interpret even-odd effects of maximum total kinetic energy as a function of mass and charge of fragments from thermal neutron induced fission of U-235. Assuming spherical fragments at scission, the Coulomb interaction energy between fragments (C_sph) is higher than the Q-value, the available energy. Therefore at scission the fragments must be deformed, so that the Coulomb interaction energy does not exceed the Q-value. The fact that the even-odd effects in the maximum total kinetic energy as a function of the charge and mass, respectively, are lower than the even-odd effects of Q is consistent with the assumption that odd mass fragments are softer than the even-even fragments. Even-odd effects of charge distribution in super asymmetric fragmentation also are interpreted with the Coulomb effect hypothesis. Because the difference between C_sph and Q increases with asymmetry, fragmentations require higher total deformation energy to occur. Higher deformation energy of the fragments implies lower free energy to break pairs of nucleons. This explains why in the asymmetric fragmentation region, the even-odd effects of the distribution of proton number and neutron number increases with asymmetry. Based on a similar reasoning, a prediction of a relatively high even-odd effect in symmetric fragmentations is proposed.