Se determinó el espectro de acción de las sustancias activas producido por 27 cepas de bacterias marinas inhibidoras de Staphylooccus aureus ATCC 6538 contra bacterias patógenas en animales, realizando antibiogramas con concentraciones bacterianas similares (patrón Me Farland 0,5). De 27 cepas utilizadas, 3 (11,11%) mostraron actividad en alguna bacteria patógena estudiada. Las cepas patógenas para animales Rhodococcus equi, Listeria monocytogenes y Brucella abortus resultaron ser las más afectadas por las sustancias antibacterianas y la cepa Staphylococcus aureus (aislada de Gallus gallus) la menos afectada. La sustancia activa producida por la cepa marina Chromobacterium sp. SnSF(30)27498 aislada del coral Stephanocoenia michelinii, evidenció un efecto inhibitorio en todas las bacterias patógenas estudiadas (100%); esta sustancia conjuntamente con la producida por la cepa Chromobacterium sp. PaSF(48)27498 aislada del coral Porites asteroides mostraron los mayores halos de inhibición contra las patógenas para animales. Basados en los resultados obtenidos, se consideró que las bacterias marinas poseen un gran potencial para la búsqueda de sustancias activas ante bacterias patógenas para animales de cría.189 - 193BimestralActive substances were taken from 27 strains of marine bacteria that inhibit the germ Staphylococcus aureus ATCC 6538, which is pathogenic to human beings. The spectrum of action against bacteria that are pathogenic to animals were determined through the use of antibiograms with similar bacteria) concentrations (0.5 Me Farland pattern). Among the 27 strains studied, 3 of them (11.11 %) were active against some pathogenic bacteria. The strains of Rhodococcus equi, Listeria monocytogenes and Brucella abortus, pathogenic against animals, were the most affected by the antibacterial substances, and the strain Staphylococcus aureus (isolated from Gallus gallus) was the least affected. The active substance produced by the marine strain Chromobacterium sp. SnSF(30)27498 (isolated from the coral Stephanocoenia michelinii) inhibited 100% of the pathogenic bacteria. This substance, as well as the substance produced by the strain Chromobacterium sp. PaSF(48)27498 (isolated from the coral Porites astreoides) showed the largest inhibition halos against bacteria that are pathogenic to animals. In view of these results, marine bacteria are considered to have a great potential for producing active substances against bacteria that are pathogenic to animals.