Argentina
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Sustainable Synthesis of Flavonoid Derivatives, QSAR Study and Insecticidal Activity against the Fall Armyworm, Spodoptera frugiperda (Lep.: Noctuidae)
Fecha
2010-05Registro en:
Romanelli, Gustavo Pablo; Virla, Eduardo Gabriel; Duchowicz, Pablo Román; Gaddi, Ana Laura; Ruiz, Diego Manuel; et al.; Sustainable Synthesis of Flavonoid Derivatives, QSAR Study and Insecticidal Activity against the Fall Armyworm, Spodoptera frugiperda (Lep.: Noctuidae); American Chemical Society; Journal of Agricultural and Food Chemistry; 58; 10; 5-2010; 6290-6295
0021-8561
CONICET Digital
CONICET
Autor
Romanelli, Gustavo Pablo
Virla, Eduardo Gabriel
Duchowicz, Pablo Román
Gaddi, Ana Laura
Ruiz, Diego Manuel
Bennardi, Daniel Oscar
Ortiz, Erlinda del Valle
Autino, Juan Carlos
Resumen
A simple, clean, solvent-free preparation of flavones by the use of a silica-supported Preyssler heteropolyacid as reusable catalyst is described. High selectivity and very good yields (87−94%) were obtained in short reaction times (7−13 min). Bioassays for insecticidal activity against Spodoptera frugiperda were carried out with a set of flavones. Bioassays showed that some of the flavones had moderate insecticidal activity. Quantitative structure−activity relationships were established on the available data with the purpose of predicting the insecticidal activity of a number of structurally related flavones. A relationship between the molecular structure and biological activity is proposed.