Artículos de revistas
Antioxidant Neolignans from Cordia americana
Fecha
2013-12Registro en:
Fernandez, Lucia Raquel; Cirigliano, Adriana Monica; Fabani, Maria Paula; Lima, Beatriz Viviana; Alberti, Sebastián; et al.; Antioxidant Neolignans from Cordia americana; Georg Thieme Verlag Kg; Planta Medica; 79; 18; 12-2013; 1724-1729
0032-0943
CONICET Digital
CONICET
Autor
Fernandez, Lucia Raquel
Cirigliano, Adriana Monica
Fabani, Maria Paula
Lima, Beatriz Viviana
Alberti, Sebastián
Kramer, Fernando Luis
Tapia, Alejandro A.
Cabrera, Gabriela Myriam
Palermo, Jorge Alejandro
Sánchez, Marianela
Resumen
Five new neolignans with a bicyclo[2.2.2]octene framework were isolated from an ethanolic extract of the bark of Cordia americana. The structures and relative configurations of the compounds were elucidated by a combination of spectroscopic methods. All the isolated compounds showed good antioxidant activities in the DPPH radical scavenging (0.5–100 µg/mL) and Ferric-reducing antioxidant power (FRAP, 1–100 µg/mL) assays. One of the compounds displayed mild fungistatic activity at 0.1 µmol/spot against Fusarium virguliforme while, at the same time, all compounds were inactive against several strains of Gram (+) and Gram (−) bacteria at all assayed concentrations (10–1000 µg/mL).