info:eu-repo/semantics/article
Spinal cord injury drives chronic brain changes
Fecha
2017-07Registro en:
Jure, Ignacio; Labombarda, Maria Florencia; Spinal cord injury drives chronic brain changes; Shenyang Editorial Dept Neural Regeneration Res; Neural Regeneration Research; 12; 7; 7-2017; 1044-1047
1673-5374
1876-7958
CONICET Digital
CONICET
Autor
Jure, Ignacio
Labombarda, Maria Florencia
Resumen
Only a few studies have considered changes in brain structures other than sensory and motor cortex after spinal cord injury, although cognitive impairments have been reported in these patients. Spinal cord injury results in chronic brain neuroinflammation with consequent neurodegeneration and cognitive decline in rodents. Regarding the hippocampus, neurogenesis is reduced and reactive gliosis increased. These longterm abnormalities could explain behavioral impairments exhibited in humans patients suffering from spinal cord trauma.