Comparative Efficacies of TAK-187, a Long-Lasting Ergosterol Biosynthesis Inhibitor, and Benznidazole in Preventing Cardiac Damage in a Murine Model of Chagas' Disease

dc.creatorCorrales, Milagros
dc.creatorCardozo, Rubén Marino
dc.creatorSegura, Maria Asuncion
dc.creatorUrbina, Julio A.
dc.creatorBasombrío, Miguel Ángel Manuel
dc.date.accessioned2018-04-10T20:36:55Z
dc.date.available2018-04-10T20:36:55Z
dc.date.created2018-04-10T20:36:55Z
dc.date.issued2005-03
dc.identifierCorrales, Milagros; Cardozo, Rubén Marino; Segura, Maria Asuncion; Urbina, Julio A.; Basombrío, Miguel Ángel Manuel; Comparative Efficacies of TAK-187, a Long-Lasting Ergosterol Biosynthesis Inhibitor, and Benznidazole in Preventing Cardiac Damage in a Murine Model of Chagas' Disease; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 49; 4; 3-2005; 1556-1560
dc.identifier0066-4804
dc.identifierhttp://hdl.handle.net/11336/41626
dc.identifierCONICET Digital
dc.identifierCONICET
dc.description.abstractWe carried out a comparative study of benznidazole and TAK-187, a long-lasting ergosterol biosynthesis inhibitor, with a murine model of Chagas` disease. The results indicated that TAK-187 was more effective than benznidazole in preventing Trypanosoma cruzi-induced cardiac damage in experimental animals.
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://aac.asm.org/content/49/4/1556.long
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1128/AAC.49.4.1556-1560.2005
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTak-187
dc.subjectTrypanosoma Cruzi
dc.subjectBenznidazole
dc.subjectCardiac Damage
dc.titleComparative Efficacies of TAK-187, a Long-Lasting Ergosterol Biosynthesis Inhibitor, and Benznidazole in Preventing Cardiac Damage in a Murine Model of Chagas' Disease
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


Este ítem pertenece a la siguiente institución