Ex Vivo Loading of Autologous Dendritic Cells with Tumor Antigens

dc.creatorRizzo, Manglio Miguel
dc.creatorAlaniz, Laura Daniela
dc.creatorMazzolini Rizzo, Guillermo Daniel
dc.date.accessioned2018-01-09T18:38:23Z
dc.date.available2018-01-09T18:38:23Z
dc.date.created2018-01-09T18:38:23Z
dc.date.issued2014-02
dc.identifierRizzo, Manglio Miguel; Alaniz, Laura Daniela; Mazzolini Rizzo, Guillermo Daniel; Ex Vivo Loading of Autologous Dendritic Cells with Tumor Antigens; Springer; Methods in Molecular Biology (clifton, N.j.); 2-2014; 41-44
dc.identifier1064-3745
dc.identifierhttp://hdl.handle.net/11336/32687
dc.identifierCONICET Digital
dc.identifierCONICET
dc.description.abstractEx vivo-generated antigen-loaded dendritic cells (DC) have been shown to be immunogenic in patients with cancer. Loading DC with autologous whole tumor antigens is a strategy to arm DC against tumor without human leukocyte antigen (HLA) restriction. Furthermore, this approach allows the presentation of a full antigen range to the immune system. We describe the methods to obtain whole antigens from autologous tumor tissues in order to load DC generated ex vivo from patients with gastrointestinal cancer.
dc.languageeng
dc.publisherSpringer
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://link.springer.com/protocol/10.1007/978-1-4939-0345-0_5
dc.relationPart of the Methods in Molecular Biology book series (MIMB, volume 1139)
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectDendritic Cells
dc.subjectCancer
dc.subjectVaccines
dc.subjectProtocol
dc.subjectTumor Specimen
dc.subjectAutologous Tumor Tissue
dc.titleEx Vivo Loading of Autologous Dendritic Cells with Tumor Antigens
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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