Artículos de revistas
Diffuse reflectance optical topography: location of inclusions in 3D and detectability limits
Fecha
2014-03Registro en:
Carbone, Nicolás Abel; Baez, Guido Rodrigo; García, Héctor Alfredo; Waks Serra, María Victoria; Di Rocco, Hector Omar; et al.; Diffuse reflectance optical topography: location of inclusions in 3D and detectability limits; Optical Society of America; Biomedical Optics Express; 5; 5; 3-2014; 1336-1354
2156-7085
Autor
Carbone, Nicolás Abel
Baez, Guido Rodrigo
García, Héctor Alfredo
Waks Serra, María Victoria
Di Rocco, Hector Omar
Iriarte, Daniela Ines
Pomarico, Juan Antonio
Grosenick, D.
Macdonald, R.
Resumen
In the present contribution we investigate the images of CW diffusely reflected light for a point-like source, registered by a CCD camera imaging a turbid medium containing an absorbing lesion. We show that detection of μa variations (absorption anomalies) is achieved if images are normalized to background intensity. A theoretical analysis based on the diffusion approximation is presented to investigate the sensitivity and the limitations of our proposal and a novel procedure to find the location of the inclusions in 3D is given and tested. An analysis of the noise and its influence on the detection capabilities of our proposal is provided. Experimental results on phantoms are also given, supporting the proposed approach.