info:eu-repo/semantics/article
Dual role of astrocytes in perinatal asphyxia injury and neuroprotection
Fecha
2013-10Registro en:
Romero, Juan Ignacio; Muñiz, Javier Andrés; Logica Tornatore, Tamara Maite Ayelén; Holubiec, Mariana Ines; González, Janneth; et al.; Dual role of astrocytes in perinatal asphyxia injury and neuroprotection; Elsevier Ireland; Neuroscience Letters; 565; 10-2013; 42-46
0304-3940
CONICET Digital
CONICET
Autor
Romero, Juan Ignacio
Muñiz, Javier Andrés
Logica Tornatore, Tamara Maite Ayelén
Holubiec, Mariana Ines
González, Janneth
Barreto, George E.
Guelman, Laura Ruth
Lillig, Christhopher Horst
Blanco, E.
Capani, Francisco
Resumen
Perinatal asphyxia represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness. However, at the moment, most of the therapeutic strategies were not well targeted toward the processes that induced the brain injury during perinatal asphyxia. Traditionally, experimental research focused on neurons, whereas astrocytes have been more related with the damage mechanisms of perinatal asphyxia. In this work, we propose to review possible protective as well as deleterious roles of astrocytes in the asphyctic brain with the aim to stimulate further research in this area of perinatal asphyxia still not well studied.