Artículos de revistas
Blood pressure long term regulation: a neural network model of the set point development
Fecha
2011-06Registro en:
Zanutto, Bonifacio Silvano; Cernuschi Frias, Bruno; Valentinuzzi, Max E.; Blood pressure long term regulation: a neural network model of the set point development; BioMed Central; Biomedical Engineering Online; 10; 10; 6-2011; 1-15
1475-925X
Autor
Zanutto, Bonifacio Silvano
Cernuschi Frias, Bruno
Valentinuzzi, Max E.
Resumen
The notion of the nucleus tractus solitarius (NTS) as a comparator evaluating the error signal between its rostral neural structures (RNS) and the cardiovascular receptor afferents into it has been recently presented. From this perspective, stress can cause hypertension via set point changes, so offering an answer to an old question. Even though the local blood flow to tissues is influenced by circulating vasoactive hormones and also by local factors, there is yet significant sympathetic control. It is well established that the state of maturation of sympathetic innervation of blood vessels at birth varies across animal species and it takes place mostly during the postnatal period. During ontogeny, chemoreceptors are functional; they discharge when the partial pressures of oxygen and carbon dioxide in the arterial blood are not normal.