Artículos de revistas
Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina
Fecha
2013-09Registro en:
de Matteo, Elena Noemí; Lara, María Julia; Preciado, María Victoria; Cohen, Melina; Chabay, Paola Andrea; Aversa, Luis; et al.; Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina; Wiley; Journal of Medical Virology; 86; 5; 9-2013; 845-850
0146-6615
CONICET Digital
CONICET
Autor
Lara, María Julia
Cohen, Melina
de Matteo, Elena Noemí
Aversa, Luis
Preciado, María Victoria
Chabay, Paola Andrea
Resumen
The aim of this study is to characterise EBV expression and latency pattern in paediatric Burkitt lymphoma in a single institution in Argentina. EBV-encoded RNA or protein was analyzed in 27 patients. EBERs was expressed in 37% of patients (29% of immunocompetent and 100% of immunosuppressed patients). EBV-positive cases were observed exclusively in patients younger than 5 years old. EBV association with immunocompetent patients exhibits the sporadic pattern in region under study, while its presence in patients infected with HIV was higher than described previously. EBV latency I profile was present in most of the patients, except for 2 immunosuppressed patients who displayed LMP1 expression.