info:eu-repo/semantics/article
Augmented serum levels of the IGF-I/IGFBP3 ratio in pre-menopausal patients with type I breast cysts
Fecha
2003-02Registro en:
Enriori, Pablo J.; Fischer, Carlos R.; Gori, Jorge R.; Etkin, Alberto E.; Calandra, Ricardo Saul; et al.; Augmented serum levels of the IGF-I/IGFBP3 ratio in pre-menopausal patients with type I breast cysts; BioScientifica; European Journal of Endocrinology; 148; 2; 2-2003; 177-184
0804-4643
1479-683X
CONICET Digital
CONICET
Autor
Enriori, Pablo J.
Fischer, Carlos R.
Gori, Jorge R.
Etkin, Alberto E.
Calandra, Ricardo Saul
Luthy, Isabel Alicia
Resumen
Gross cystic disease (GCD) is the most common benign breast pathology. Although breast cysts are not considered pre-malignant lesions, an increased risk of breast cancer has been reported for patients with type I cysts (Na(+)/K(+)<3). Furthermore, an augmented IGF-I/IGF-binding protein-3 (IGFBP-3) ratio has been described in breast cancer patients. The objective was to evaluate serum IGF-I and binding protein concentrations of type I and type II cyst patients as compared with healthy women.