Artículos de revistas
Base-Free Direct Synthesis of Alkynylphosphonates from Alkynes and H-Phosphonates Catalyzed by Cu2O
Fecha
2016-03-04Registro en:
Moglie, Yanina Fernanda; Mascaro, Evangelina; Gutierrez, Victoria Soledad; Alonso, Francisco; Radivoy, Gabriel Eduardo; Base-Free Direct Synthesis of Alkynylphosphonates from Alkynes and H-Phosphonates Catalyzed by Cu2O; American Chemical Society; Journal of Organic Chemistry; 81; 5; 4-3-2016; 1813-1818
0022-3263
CONICET Digital
CONICET
Autor
Moglie, Yanina Fernanda
Mascaro, Evangelina
Gutierrez, Victoria Soledad
Alonso, Francisco
Radivoy, Gabriel Eduardo
Resumen
A simple and mild methodology for the direct synthesis of alkynylphosphonates is presented. The reaction of a variety of terminal alkynes with dialkyl phosphites in the presence Cu2O (14 mol %) led to the formation of the corresponding alkynylphosphonates in good to excellent yields. Reactions are performed under air, in acetonitrile as solvent, and in the absence of base or ligand additives. This new methodology is compatible with the presence of a wide variety of functional groups on the starting alkynes and can be scaled up to a gram scale.