Artículos de revistas
Rapid identification of OXA-48 and OXA-163 subfamily in carbapenem resistant gram-negative bacilli with a novel immunochromatographic lateral flow assay
Fecha
2016-08Registro en:
Pasteran, Fernando; Denorme, Laurence; Ote, Isabelle; Gómez, Sonia Alejandra; de Belder, Denise Gisele; et al.; Rapid identification of OXA-48 and OXA-163 subfamily in carbapenem resistant gram-negative bacilli with a novel immunochromatographic lateral flow assay; American Society for Microbiology; Journal of Clinical Microbiology; 54; 11; 8-2016; 2832-2836
0095-1137
CONICET Digital
CONICET
Autor
Pasteran, Fernando
Denorme, Laurence
Ote, Isabelle
Gómez, Sonia Alejandra
de Belder, Denise Gisele
Glupczynsk, Youri
Bogaerts, Pierre
Ghiglione, Barbara
Power, Pablo
Mertens, Pascal
Corso, Alejandra
Resumen
We assessed a novel immunochromatographic lateral flow assay for direct identification of OXA-48-like carbapenemases and accurate differentiation of allele variants with distinct substrate profiles (OXA-48 or OXA-163 subfamilies). The assay allowed rapid (less than 4 min) and reliable direct confirmation of OXA-163- and/or OXA-48-like enzymes (with 100% sensitivity and 100% specificity) from cultured colonies that were recovered from both solid medium and spiked blood culture bottles.