H1 and H2 histamine receptors mediate the production of inositol phosphates but not cAMP in human breast epithelial cells

Davio, Carlos Alberto; Mladovan, Alejandro Guillermo; Lemos, Bibiana; Monczor, Federico; Shayo, Carina Claudia; Rivera E.; Baldi, Alberto

Artículos de revistas

Fecha

2002-10

Registro en:

Monczor, Federico; Lemos, Bibiana; Mladovan, Alejandro Guillermo; Davio, Carlos Alberto; Baldi, Alberto; Rivera E.; et al.; H1 and H2 histamine receptors mediate the production of inositol phosphates but not cAMP in human breast epithelial cells; Birkhauser Verlag Ag; Inflammation Research; 51; 1; 10-2002; 1-7

1023-3830

http://hdl.handle.net/11336/31333

1420-908X

CONICET Digital

CONICET

http://repositorioslatinoamericanos.uchile.cl/handle/2250/1876538

Autor

Davio, Carlos Alberto

Mladovan, Alejandro Guillermo

Lemos, Bibiana

Monczor, Federico

Shayo, Carina Claudia

Rivera E.

Baldi, Alberto

Institución

Consejo Nacional de Investigaciones Científicas y Tecnológicas (Argentina)

Resumen

In the present work we studied the histamine receptor expression and function in HBL-100 and MCF-10A cells, derived from non-tumorigenic human breast epithelia, and in MCF-10T, the H-ras-transfected MCF-10A counterpart. The signal transduction pathways associated with these receptors, and the expression of proto-oncogenes c-fos, c-myc and c-jun at the mRNA and protein levels, were examined.

Materias

SIGNAL TRANSDUCTION

C-MYC

C-FOS

HUMAN EPITHELIAL CELLS

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