Artículos de revistas
Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T
Fecha
2015-01Registro en:
Martinez, Mario David; Rustoy, Eduardo Miguel; Raggio, Norberto; Burton, Gerardo; Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T; Elsevier Science; Inorganic Chemistry Communications; 51; 1-2015; 110-113
1387-7003
CONICET Digital
CONICET
Autor
Martinez, Mario David
Rustoy, Eduardo Miguel
Raggio, Norberto
Burton, Gerardo
Resumen
In this study a novel ligand with three carboxylic groups (H3L1 ) was synthesized. Its non-ion complex with GdL1 holding promise of magnetic resonance imaging (MRI) was synthesized, and the relaxivity of the complex determined. The relaxivity of GdL1 (R1 = 4.5 Mmol−1 ·s−1 ) was larger than that of Gd(DTPA)2−(R1 = 3.9 Mmol−1 ·s−1 ). The results showed that the non-ion complex is a prospective MRI contrast agent.