info:eu-repo/semantics/article
QnrE1, a member of a new family of plasmid-located quinolone resistance genes, originated from the chromosome of enterobacter species
Fecha
2017-05Registro en:
Albornoz, Ezequiel Pablo; Tijet, Nathalie; de Belder, Denise Gisele; Gómez, Sonia Alejandra; Martino, Florencia; et al.; QnrE1, a member of a new family of plasmid-located quinolone resistance genes, originated from the chromosome of enterobacter species; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 61; 5; 5-2017; 1-8
0066-4804
CONICET Digital
CONICET
Autor
Albornoz, Ezequiel Pablo
Tijet, Nathalie
de Belder, Denise Gisele
Gómez, Sonia Alejandra
Martino, Florencia
Corso, Alejandra
Melano, Roberto G.
Petroni, Alejandro
Resumen
qnrE1, found in a clinical Klebsiella pneumoniae isolate, was undetectable by PCR assays used for the six qnr families. qnrE1 was located on a conjugative plasmid (ca. 185 kb) and differed from qnrB alleles by 25%. Phylogenetic reconstructions of qnr genes and proteins and analysis of the qnrE1 surroundings showed that this gene belongs to a new qnr family and was likely mobilized by ISEcp1 from the chromosome of Enterobacter spp. to plasmids of K. pneumoniae.