Artículos de revistas
Antidepressants: Influence on cancer and immunity?
Fecha
2013-01-28Registro en:
Frick, Luciana Romina; Rapanelli, Maximiliano; Antidepressants: Influence on cancer and immunity?; Elsevier; Life Sciences; 92; 10; 28-1-2013; 525-532
0024-3205
1879-0631
Autor
Frick, Luciana Romina
Rapanelli, Maximiliano
Resumen
Two decades ago, it was hypothesized that antidepressants could alter the course of neoplastic diseases. However, contradictory findings indicated that antidepressants could either have carcinogenic properties or improve the disease outcome. Intriguingly, controversial results were reported on the action of antidepressant drugs on immune function. Further hypotheses proposed that antidepressants could indirectly affect the cancer prognosis through the modulation of antitumor activity. Here we review the literature in order to elucidate the influence of antidepressants on cancer and immunity.