info:eu-repo/semantics/article
Bioactivity of the essential oil of an argentine collection of acanthospermum hispidum (asteraceae)
Fecha
2012-02Registro en:
Alva, Mariana; Popich, Susana Beatriz; Borkosky, Susana Alicia; Cartagena, Elena; Bardon, Alicia del Valle; Bioactivity of the essential oil of an argentine collection of acanthospermum hispidum (asteraceae); Natural Products; Natural Product Communications; 7; 2; 2-2012; 245-248
1934-578X
CONICET Digital
CONICET
Autor
Alva, Mariana
Popich, Susana Beatriz
Borkosky, Susana Alicia
Cartagena, Elena
Bardon, Alicia del Valle
Resumen
The essential oil of an Argentine collection of the annual herb Acanthospermum hispidum DC. (Asteraceae), which contains the sesquiterpenoids beta-caryophyllene (35.2%), alpha-bisabolol (11.4%), and germacrene D (11.1%) as major constituents, displayed molluscicidal effects on an adult population of Biomphalaria peregrina Orbigny (LD50 37.8 μg/mL) and produced alteration of the feeding and oviposition behavior of the polyphagous insect Spodoptera frugiperda Smith when incorporated in the larval diet at 250 μg/g. In addition, a selective antibacterial activity was observed against pathogenic strains of Staphylococcus aureus and Enterococcus faecalis (MICs 62.5 and 125 μg/mL), but was inactive at 125 μg/mL against three beneficial lactic acid bacteria. Synergistic interactions were further validated by FIC index determination of the combination of the antibiotics oxacillin and gentamicin and the essential oil on the four pathogenic strains evaluated.