Artículos de revistas
Synthesis of a 3-Thiomannoside
Fecha
2016-04Registro en:
Comba, María Betina; Suarez, Alejandra Graciela; Sarotti, Ariel Marcelo; Mangione, Maria Ines; Spanevello, Rolando Angel; et al.; Synthesis of a 3-Thiomannoside; American Chemical Society; Organic Letters; 18; 8; 4-2016; 1748-1751
1523-7060
CONICET Digital
CONICET
Autor
Comba, María Betina
Suarez, Alejandra Graciela
Sarotti, Ariel Marcelo
Mangione, Maria Ines
Spanevello, Rolando Angel
Giordano, Enrique David Victor
Resumen
An efficient and straightforward synthesis of a novel 3-thiomannoside derivative (1,2,4,6-tetra-O-acetyl-3-S-acetyl-3-thio-β-d-mannopyranoside) was developed starting from levoglucosenone. A xanthate-thiocarbonate exchange under acidic conditions was the key step for the new C-S bond. The product was obtained enantiospecifically in very good overall yield.