Artículos de revistas
Reassessment of genotype 1 hepatitis c virus subtype misclassification by LiPA 2.0: implications for direct-acting antiviral treatment
Fecha
2014-11Registro en:
Guelfo, Javier R.; Macias, Juan; Neukam, Karin; Di Lello, Federico Alejandro; Mira José Antonio; et al.; Reassessment of genotype 1 hepatitis c virus subtype misclassification by LiPA 2.0: implications for direct-acting antiviral treatment; American Society for Microbiology; Journal of Clinical Microbiology; 52; 11; 11-2014; 4027-4029
0095-1137
Autor
Guelfo, Javier R.
Macias, Juan
Neukam, Karin
Di Lello, Federico Alejandro
Mira José Antonio
Merchante, Nicolás
Mancebo, María
Nuñez Torres, Rocío
Pineda, Juan A.
Real. Luis M.
Resumen
The accuracy of LiPA 2.0 for hepatitis C virus 1 (HCV-1) subtype classification was analyzed. LiPA 2.0 genotype results from 101 HCV-1-infected patients were compared to genotype findings determined by direct core sequencing. Eleven (11%) samples were misclassified. Given the influence of the HCV-1-subtype in the anti-HCV therapy response, an alternative classification method is warranted.