Artículos de revistas
Use of a Melanin-Type Polymer to Improve the Selectivity of Glucose Biosensors
Fecha
2003-01-02Registro en:
Rubianes, María Dolores; Rivas, Gustavo Adolfo; Use of a Melanin-Type Polymer to Improve the Selectivity of Glucose Biosensors; Taylor ; Analytical Letters; 36; 7; 2-1-2003; 1311-1323
0003-2719
1532-236X
CONICET Digital
CONICET
Autor
Rubianes, María Dolores
Rivas, Gustavo Adolfo
Resumen
This paper reports the advantages of using a melanin-type polymer to improve the selectivity of glucose biosensors based on carbon paste electrodes containing Pt and glucose oxidase (GOx). The resulting bioelectrodes combine the high sensitivity of metallized electrodes with the selectivity given by the polymeric layer. They exhibit excellentperformance for glucose with a rapid response (around 10 sec per sample), a wide linear range (up to 3.0 10 2 M), low detection limits (60 mM) and a highly reproducible response (R.S.D. of 4.9%). The bioelectrodes are stable with prolonged use and almost free from the interference of easily oxidizable compounds found inbiological fluids, such as ascorbic acid (AA), uric acid (UA) and acetaminophen.