Artículos de revistas
Does reconsolidation occur in natural settings? Memory reconsolidation and anxiety disorders
Fecha
2017-11Registro en:
Fernández, Rodrigo Sebastián; Pedreira, Maria Eugenia; Boccia, Mariano Martín; Does reconsolidation occur in natural settings? Memory reconsolidation and anxiety disorders; Elsevier; Clinical Psychology Review; 57; 11-2017; 45-58
0272-7358
CONICET Digital
CONICET
Autor
Fernández, Rodrigo Sebastián
Pedreira, Maria Eugenia
Boccia, Mariano Martín
Resumen
In normal settings, our brain is able to update its stored representations in content, strength, and/or expectations by the memory reconsolidation process. Thus, a reactivated memory enters in a transient labile state (destabilization) followed by a re-stabilization phase in order to persist (memory reconsolidation). Cognitive neuroscience and its insight into psychiatric problems attributed a close relationship between memory (formation, maintenance, and utilization) and several mental disorders. In this framework, the reconsolidation process could be not only the mechanism for maintenance of some psychopathologies, but also open a novel therapeutic window. Here we aim to integrate integrate recent experimental and theoretical research on memory reconsolidation and anxiety disorders maintenance. We propose a bayesian-like model about anxiety disorders persistence and postulate a new theoretical framework for how anxiety disorders are maintained through impaired memory updating due to a dysfunctional prediction error minimization strategy and anticipatory responses to threat.