Artículos de revistas
L-Phenylalanine Transport in Saccharomyces cerevisiae: Participation of GAP1, BAP2, and AGP1
Fecha
2014-02Registro en:
Stella, Carlos Alberto; Chianelli, Monica Silvia; Saenz, Daniel Alberto; L-Phenylalanine Transport in Saccharomyces cerevisiae: Participation of GAP1, BAP2, and AGP1; Hindawi Publishing Corporation; Journal of Amino Acids; 2014; 2-2014; 283962-283970
2090-0104
Autor
Stella, Carlos Alberto
Chianelli, Monica Silvia
Saenz, Daniel Alberto
Resumen
We focused on the participation of GAP1, BAP2, andAGP1 in L-phenylalanine transport in yeast. In order to study the physiological functions of GAP1, BAP2, and AGP1 in L-phenylalanine transport, we examined the kinetics, substrate specificity, and regulation of these systems, employing isogenic haploid strains with the respective genes disrupted individually and in combination. During the<br />characterization of phenylalanine transport, we noted important regulatory phenomena associated with these systems. Our results show that Agp1p is the major transporter of the phenylalanine in a gap1 strain growing in synthetic media with leucine present as an inducer. In a wild type strai