Artículos de revistas
Solid-supported cross-metathesis and a formal alkane metathesis for the generation of biologically relevant molecules
Fecha
2015-02Registro en:
Mendez, Luciana; Mata, Ernesto Gabino; Solid-supported cross-metathesis and a formal alkane metathesis for the generation of biologically relevant molecules; American Chemical Society; ACS Combinatorial Science; 17; 2; 2-2015; 81-86
2156-8952
Autor
Mendez, Luciana
Mata, Ernesto Gabino
Resumen
Solid-phase synthetic strategies towards the generation of libraries of biologically relevant molecules were developed using olefin cross-metathesis as a key step. It is remarkably the formal alkane metathesis based on a one-pot, microwave-assisted, ruthenium catalyzed cross-metathesis and reduction to obtain Csp3-Csp3 linkages