Artículos de revistas
Virtual Monochromatic Imaging in Patients with Intermediate to High Likelihood of Coronary Artery Disease: Impact of Coronary Calcification
Fecha
2016-12Registro en:
Carrascosa, Patricia; Leipsic, Jonathon A.; Deviggiano, Alejandro; Capunay, Carlos; Vallejos, Javier; et al.; Virtual Monochromatic Imaging in Patients with Intermediate to High Likelihood of Coronary Artery Disease: Impact of Coronary Calcification; Elsevier Science Inc; Academic Radiology; 23; 12; 12-2016; 1490-1497
1076-6332
CONICET Digital
CONICET
Autor
Carrascosa, Patricia
Leipsic, Jonathon A.
Deviggiano, Alejandro
Capunay, Carlos
Vallejos, Javier
Goldsmit, Alejandro
De Zan, Macarena
Rodriguez Granillo, Gaston Alfredo
Resumen
Rationale and Objectives
We sought to explore the image quality and diagnostic performance of virtual monochromatic imaging derived from dual-energy computed tomography coronary angiography (DE-CTCA) in patients with intermediate to high likelihood of coronary artery disease (CAD) and the influence of calcification.
Materials and Methods
Consecutive symptomatic patients with suspected CAD referred for invasive coronary angiography who underwent DE-CTCA and a coronary artery calcium scoring before the invasive procedure comprised the study population.
Results
Sixty-seven patients were included. Image quality was significantly lower at 45 keV reconstructions (mean Likert score 45 keV 3.57 ± 0.6, 65 keV 4.07 ± 0.5, and 85 keV 4.09 ± 0.6; P < .0001). Patients with moderate calcification showed a trend toward a significant improvement in the diagnostic performance with 65 keV vs 45 keV reconstructions (45 keV, area under the curve 0.92 [95% confidence interval 0.89–0.95] vs 65 keV, area under the curve 0.96 [95% confidence interval 0.93–0.98], P = .06). The diagnostic performance of DE-CTCA was significantly lower in segments with higher coronary artery calcium scoring compared to segments with none or mild calcification, independent of the energy level applied.
Conclusions
In patients with intermediate to high likelihood of CAD, DE-CTCA had a good diagnostic performance, although significantly lower in segments with severe calcification.