info:eu-repo/semantics/article
Aetiology, epidemiology and clinical characteristics of acute moderate-to-severe diarrhoea in children under 5 years of age hospitalized in a referral paediatric hospital in Rabat, Morocco
Fecha
2015-01-09Registro en:
1. Benmessaoud R, Jroundi I, Nezha M, Moraleda C, Tligui H, Seffar M, et al. Aetiology, epidemiology and clinical characteristics of acute moderate-to-severe diarrhoea in children under 5 years of age hospitalized in a referral paediatric hospital in Rabat, Morocco. J Med Microbiol. enero de 2015;64(Pt 1):84-92.
0022-2615
10.1099/jmm.0.079830-0
1473-5644
Journal of Medical Microbiology (J Med Microbiol.)
Autor
Benmessaoud, R
Jroundi, I
Nezha, M
Moraleda, C
Tligui, H
Seffar, M
Alvarez Martínez, MJ
Pons, Maria J
Chaacho, S
Hayes, EB
Vila, J
Alonso,PL
Bassat, Q
Ruiz, J
Institución
Resumen
The objective of the study was to describe the aetiology, epidemiology and clinical characteristics of the principal causes of acute infectious diarrhoea requiring hospitalization among children under 5 years of age in Rabat, Morocco. A prospective study was conducted from March 2011 to March 2012, designed to describe the main pathogens causing diarrhoea in hospitalized children >2 months and less than 5 years of age. Among the 122 children included in the study, enteroaggregative Escherichia coli (EAEC) and rotavirus were the main aetiological causes of diarrhoea detected. Twelve (9.8 %) children were referred to an intensive care unit, while two, presenting infection by EAEC, and EAEC plus Shigella sonnei, developed a haemolytic uraemic syndrome. Additionally, six (4.9 %) deaths occurred, with EAEC being isolated in four of these cases. Diarrhoeagenic E. coli and rotavirus play a significant role as the two main causes of severe diarrhoea, while other pathogens, such as norovirus and parasites, seem to have a minimal contribution. Surveillance and prevention programmes to facilitate early recognition and improved management of potentially life-threatening diarrhoea episodes are needed.