Actas de congresos
Investigation of the electronic and magnetic hyperfine properties of the copper(II) and zinc(II) complexes.
Fecha
2014-05-21Registro en:
1st Symposium on Current Topics in Molecular Biophysics, 2014, São Paulo.
Autor
Virgino, Adamor Luz Eleiel
Institución
Resumen
The treatment of cancer diseases are a dangerous world wide
problem that requires the usage of extreme techniques such as surgery and
the use of metallodrugs (pharmaceutical metal complexes). The most famous
antitumor metal complex is the cisplatin but it has several collateral effects
that cause injuries in the patients. This opens opportunity to research and
develop alternatives that could increase the efficiency or reduce the body
damage. However, metal complexes are a difficult class of compound to deal
with, often requiring theoretical methods to guide the characterization of the
molecules. We investigate the electronic and magnetic hyperfine properties
of the copper(ll) and zinc(ll) complexes of 2(3H)- Furanone,dihydro-3-
(hydroxyphenylmethyl)-4-[(1-methyl-1 H-imidazol-4-yl)methyi]-,[3S[
3a(R*),4b]] (Epiisopiloturine) metal complex, an alkaloid that show activity
against cancer and schistosomiasis.